ncRNA name | hsa-miR-34a |
ncRNA Category | miRNA |
Disease name | proliferative vitreoretinopathy (PVR) |
Species | Homo sapiens |
Tissues/Cell_line | human RPE cell line ARPE-19 |
Methods | immunofluorescence staining, qPCR, WST-1 assay, TUNEL assay, transwell assay, in vitro scratch assay, Western blot |
Expression pattern | down-regulated |
Functional description | MicroRNA-34a can inhibit the proliferation and migration of RPE cells through downregulation of its targets c-Met and other cell cycle-related molecules. |
PubMed ID | 23970470 |
Year | 2013 |
Title | Inhibitory effect of microRNA-34a on retinal pigment epithelial cell proliferation and migration. |
Drug-related ncRNA | NO |
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